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Cancer Research

Cancer Research

Breastlink is committed to working with research partners to help improve our ability to detect and treat breast cancer. Breast cancer research news from our practices

Breastlink Partners with Researchers to Explore Atezolizumab in Triple-Negative Breast Cancer Patients

Breastlink has partnered with researchers to explore an investigational cancer immunotherapy called atezolizumab (MPDL3280A) in the treatment of metastatic triple-negative breast cancer. In early-stage trials, atezolizmab was effective in patients previously treated for triple-negative breast cancer. A new trial will investigate atezolizumab with chemotherapy in metastatic triple-negative breast cancer patients who have not received prior systemic therapy for incurable disease. […]

By | October 19, 2015|Categories: Cancer Research, Oncology, Press Releases|0 Comments

ASCO 2015 Update: Releasing the Potential of the Immune System

The Annual Meeting of the American Society of Clinical Oncology (ASCO) provides an opportunity for thousands of oncologists and healthcare professionals to receive research updates and exchange ideas surrounding trends in cancer treatments. More than 30,000 attend each year, making it one of the largest educational and scientific conferences dedicated to advancing cancer care. I recently joined my colleagues for the ASCO 2015 Annual Meeting, where a focus was on breakthroughs in immunotherapy.

What is Immunotherapy?

Immunotherapy refers to treatments that prompt the human body’s immune system to attack cancer cells. Cancer occurs when a genetic mutations occurs that causes a healthy cell to become cancerous. Can the immune system recognize these […]

By | August 24, 2015|Categories: Cancer News, Cancer Research, Oncology|0 Comments

How Do Single-Gene & Multi-Gene Tests Compare?

The landscape of testing for hereditary cancer predisposition genes has been in rapid evolution. Recently developed tests can evaluate up to 43 genetic mutations associated with increased risk for a variety of cancers including breast cancer. Using data collected from our clinics, my Breastlink colleagues and I have analyzed how safe and effective these newer multi-gene tests are in comparison to previous methods of genetic testing.

Genetic Mutations breast cancer | gene tests

The Development of Multi-Gene Tests for Breast Cancer Risk

Two key events have helped change the face of genetic testing:

  • Technology became so advanced with next generation sequencing that it became as simple […]
By | April 30, 2015|Categories: Breast Cancer Screening, Cancer Research|Tags: , |6 Comments

SABCS 2014: ER Positive Breast Cancer Treatments

As the 37th annual San Antonio Breast Cancer Symposium (SABCS) drew to a close, a range of intriguing clinical observations and long-awaited trial updates had made the event a valuable experience for investigators and attendees alike. Among some of the most interesting updates, in my opinion, were advancements in treatments for estrogen receptor-positive (ER-positive) breast cancer, premenopausal breast cancers and advanced breast cancers.

San Antonio Breast Cancer Symposium 2014

ER Positive Breast Cancers

Results from the FERGI trial were presented at this year’s meeting. This trial is investigating the new agent pictilisib, which belong to a new class of drugs called PI3K inhibitors that […]

SABCS 2014: Breast Cancer Prevention, Screening & Genetic Testing

This year at the San Antonio Breast Cancer Symposium (SABCS) there were two aspects of breast cancer that were clearly emphasized: use of ovarian suppression in premenopausal women with breast cancer and advances in genetic testing for hereditary cancer predisposition.

San Antonio Breast Cancer Symposium 2014
Results of the SOFT trial (further detailed by Dr. Wade Smith in this post), show a clear benefit to the addition of ovarian suppression in women under the age of 35. This benefit resembles that seen with the addition of Herceptin for HER2+ cancer, and now calls for a change in practice management.

The second “call for action” released […]

SABCS 2014: Breast Cancer Radiation Therapy Preview

Every year, some of the world’s leading experts on breast cancer gather for the San Antonio Breast Cancer Symposium (SABCS). One of the premier forums on the subject, SABCS offers physicians and allied health professionals an environment conducive to the exchange of ideas and discussion around current trends in breast cancer research.

This is an excellent opportunity to meet with others passionate about breast health care, as well as to learn about new ways we can help patients. At this year’s SABCS, I am excited to learn more about the results of a trial investigating the use of radiation therapy, new markers for identifying cancer in the blood, advances in genetic […]

SABCS 2014: Estrogen Receptor Positive Treatments & More

The San Antonio Breast Cancer Symposium (SABCS) is one of the world’s premier forums on breast cancer prevention, screening and treatments. Leading experts on breast cancer from various backgrounds gather every year at the SABCS in an effort to promote discussion and education around current trends in breast cancer research.

Now in its 37th year, one of the major focuses of the 2014 SABCS will be on estrogen receptor positive breast cancer. For those interested in developments in this area and others, here is what to watch for.

San Antonio Breast Cancer Symposium 2014

Estrogen Receptor Positive Breast Cancers

In year’s past, HER2-positive breast cancers have […]

Study Reveals Lumpectomy as Safe as Mastectomy

A recent study revealed great news for women facing early-stage invasive breast cancer: choosing to preserve some breast tissue rather than removing the entire breast isn’t inviting more risk.

Survival Rate is Higher with Lumpectomy vs Mastectomy

Actually, the survival rate for women choosing lumpectomies (also referred to as Breast-Conserving Surgery) and radiation, over mastectomies is significantly higher, according to the 2013 study.

Even when coupled with various factors – age, socioeconomic status, race, tumor grade, proportion of positive nodes and year of diagnosis – women were less likely to die with a lumpectomy.

For decades, the two […]

By | September 24, 2014|Categories: Breast Surgery, Cancer Research|Tags: |0 Comments

The Importance of Breast Cancer Research

First Annual CRC Charity Golf Tournament

The Importance of Breast Cancer Research: proceeds of the first Cancer Research Collaboration Charity (CRC) Golf Tournament will be used to support ongoing efforts of the CRC and its partners to fight cancer.

The Cancer Research Collaboration is currently preparing to host its first annual CRC Charity Golf Tournament in Mission Viejo. A great chance for golfers to play a round while supporting a worthy cause and for other supporters to engage during a dinner reception, the event is sure to be a hit.

However, while we wait for the fun to begin, it is important to take a moment to remember why […]

By | September 5, 2014|Categories: Cancer Research|Tags: |0 Comments

Kadcyla Research Shows Promise in HER2 Positive Breast Cancer Treatment

Recent research into modern breast cancer therapies have driven major breakthroughs in antibody-drug conjugates, or “smart drugs,” which work by targeting cancer cells while minimizing damage to healthy body tissue.

Kadcyla, also known ado-trastuzumab emtansine (T-DM1), is one of the latest “smart drugs” 
to be FDA-approved in the treatment of women diagnosed with metastatic HER2-positive breast cancer. Kadcyla may also have potential as therapy after surgery where intent is curative.

Breastlink participated in the EMILIA trial, a key clinical trial that helped lead to swift approval of Kadcyla for HER2-positive advanced breast cancer. We also are participating in other ongoing trials to investigate additional uses for Kadcyla in […]

By | July 28, 2014|Categories: Cancer Research, Oncology|0 Comments
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