Numerous genetic mutations are linked to increased risk for breast cancer. Genetic testing can identify these mutations and guide patient management decisions. Over the past decade, multi-gene panel tests have gained traction in clinical settings. These evaluate up to 43 breast cancer-related genes, compared with limited BRCA 1 and BRCA2 (BRCA1/2) tests. In a recent review for World Journal of Surgical Procedures, I discussed whether multi-gene panel testing should replace limited BRCA1/2 testing.
Background to Genetic Testing
Since the mid-1990s, we have known about the link between BRCA1/2 and risk for breast cancer, which account for 30 to 50 percent of breast cancers. There are now well-established clinical guidelines for the […]